BoobyBiome: Giving infants a healthier start in life by boosting their gut microbiome
CPI collaborated with BoobyBiome to optimise bacterial growth conditions and establish scalable methods for producing the supplement.
The challenge
Breastfeeding difficulties such as pain and poor latch, and health complications, including mastitis and other infections that require antibiotics, are all factors that can impact access to essential breast milk bacteria.
This is why CPI collaborated with BoobyBiome, a startup translating cutting-edge breast milk research into innovative products for improving infant health.
The company approached us for support with its groundbreaking product – a next-generation supplement for babies, containing probiotic microbes isolated from breast milk and prebiotic fibres to support bacterial growth.
CPI was an excellent partner, aiding in demonstrating the manufacturing feasibility of our top bacterial candidates and distinguishing between strains in co-cultures. Their facilities in Darlington were impressive, facilitating rapid data generation. We’re now collaborating with CPI again to complete our preclinical program and prepare for the launch of our symbiotic supplement. I am excited to see this hard work translate into improved health for the next generation of infants!
Lydia Mapstone, CEO – BoobyBiome
How CPI helped
- Developed, optimised and scaled the bacterial fermentation process for product manufacture.
- Contributed microbiome therapeutics expertise.
- Provided access to state-of-the-art equipment, including high throughput bioreactor systems for process development and molecular analytical characterisation methods.
- Conducted a feasibility study on co-culturing multiple species of bacteria at scale.
Achievements
- Optimised the culture conditions for individual strains of aerobic and anaerobic bacteria.
- Developed methods to co-culture a consortium of bacteria, establishing a robust and efficient manufacturing process for a multi-strain probiotic product.
- Developed an analytical toolbox for product characterisation.
- Demonstrated the scalability and robustness of the manufacturing process at the 10L scale.
This groundbreaking solution holds immense promise for infant health and has now been shown to be both scalable and manufacturable, accelerating this product to supermarkets and hospitals in the near future.
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